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Improved Pharma’s highly successful AAPS meeting and presentation

Improved Pharma, LLC participated in the AAPS PharmSci 360 meeting in San Antonio, TX from Nov 3-6, 2019. The meeting was highly successful and allowed for several discussions surrounding our problem solving strategy.  Our booth was ideally located among several formulation companies and the formulation poster sessions, enabling a great forum for gathering scientists Read more

Improved Pharma’s highly successful AAPS meeting and presentation2020-04-30T19:01:31+00:00

Improved Pharma at AAPS with Rapid Fire Presentation, Poster, and Booth

WEST LAFAYETTE, IND. (PRWEB) SEPTEMBER 24, 2019 Improved Pharma LLC will be presenting their latest research in the area of high-level X-ray methods using synchrotron-produced X-rays to study amorphous drug formulations. On Monday, November 4th, Dr. Pamela Smith, COO of Improved Pharma, will present “Synchrotron X-Ray Diffraction and Pair Distribution Function Analysis of Drug/Polymer Dispersions: Read more

Improved Pharma at AAPS with Rapid Fire Presentation, Poster, and Booth2022-01-17T20:33:22+00:00

Poster to be presented at 2019 AAPS PharmSci 360 conference

Title: Synchrotron X-Ray Diffraction and Pair Distribution Function Analysis of Drug/Polymer Dispersions: A Comparison of Subtraction Techniques to Isolate Intra- and Intermolecular Interactions Authors: PA Smitha and SR Byrna, GLB de Araujob, CJ Benmorec Affiliations: a) Improved Pharma LLC, b) Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of Sao Paulo, c) X-ray Science Division, Read more

Poster to be presented at 2019 AAPS PharmSci 360 conference2020-04-30T19:03:18+00:00

Improved Pharma to Speak at 69th Annual Meeting of the American Crystallographic Association

WEST LAFAYETTE, IND. (PRWEB) JULY 19, 2019 Improved Pharma LLC announces the upcoming presentation of “Continuity of Solids between Amorphous and Crystalline States – Insights from Synchrotron X-ray Pair Distribution (SXPDF) Studies”. The authors are Stephen R. Byrn and Pamela A. Smith of Improved Pharma, along with Chris Benmore of Argonne National Laboratory and Gabriel Read more

Improved Pharma to Speak at 69th Annual Meeting of the American Crystallographic Association2022-01-17T20:34:19+00:00

Improved Pharma Publishes Review Article in AAPS PharmSciTech

WEST LAFAYETTE, IND. (PRWEB) JUNE 10, 2019 Improved Pharma LLC announces the publication of “Predictive and Accelerated Formulation Design Using Synchrotron Methods” in the July 2019 issue of AAPS PharmSciTech. The article was published online on April 29th, 2019. The authors are Stephen R. Byrn and Pamela A. Smith of Improved Pharma, along with Xiaoming Sean Chen of Read more

Improved Pharma Publishes Review Article in AAPS PharmSciTech2020-04-30T19:06:37+00:00

Advances in synchrotron XRPD in the pharmaceutical industry discussed at SPS-XRPD-2 and PPXRD-16

Improved Pharma and Excelsus Structural Solutions (Swiss) AG are continuing their collaboration to better enable access to synchrotron facilities for industrial clients, especially for pharmaceutical R&D.  At the conference, we discussed recent scientific advances, provided instruction on XRPD and pairwise distribution function (PDF) analysis, and facilitated discussions focused on establishing guidelines for the analysis of Read more

Advances in synchrotron XRPD in the pharmaceutical industry discussed at SPS-XRPD-2 and PPXRD-162020-04-30T19:07:13+00:00

Humidity Effects on Amorphous Pharmaceuticals

Smith1, C.J. Benmore2, J.K.R. Weber2,3 and S.R. Byrn1. 1) Improved Pharma, West Lafayette, IN 47906, USA 2) X-Ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA 3) Materials Development, Inc., Arlington Heights, IL 60004, USA The kinetics and disorder of hydration (or dehydration) of pharmaceutical hydrates is of the utmost importance Read more

Humidity Effects on Amorphous Pharmaceuticals2020-04-30T19:08:10+00:00

Improved Pharma representatives to present and teach at SPS-XRPD summit

Laboratory powder diffraction is a proven and trusted technique for pharma R&D but synchrotron powder diffraction pushes beyond the capabilities of conventional instrumentation. SPS-XRPD is joining with PPXRD to highlight the most exciting recent developments and opportunities in pharmaceutical R&D made possible by synchrotron XRPD. The joint meeting offers the chance to engage an Read more

Improved Pharma representatives to present and teach at SPS-XRPD summit2022-01-17T20:36:10+00:00

AAPS Poster – Presented at AAPS

Non-crystalline phases such as amorphous states can lead to increased solubility for drugs.  However, amorphous materials are notoriously unstable and tend to crystallize over time.  As such, many amorphous materials are created in a dispersion with a polymer to increase their physical stability.  X-ray powder diffraction patterns of amorphous materials are broad and not useful Read more

AAPS Poster – Presented at AAPS2020-04-30T19:12:07+00:00

Drug Delivery Device Summit Presentation

Current approaches to accelerated drug development typically involve parallel track activities utilizing sophisticated project management capabilities.  Improved Pharma has developed a strategy that continues to utilize these project management tools but in addition utilizes predictive tools based on structure analysis of formulations and anticipation of major instabilities of formulations by assessing formulation risk.  Orphan drugs Read more

Drug Delivery Device Summit Presentation2020-04-30T19:16:56+00:00
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