WEST LAFAYETTE, Ind., March 22, 2024 /PRNewswire-PRWeb/ -- Improved Pharma and Varda Space Industries have published the first mission results in ChemRxiv in an article entitled Return of the Ritonavir: A Study on the Stability of Pharmaceuticals Processed in Orbit and Returned to Earth. The team reports that the most stable form of ritonavir (Form II) Read more
WEST LAFAYETTE, Ind., Jan. 26, 2024 /PRNewswire-PRWeb/ -- Research for low-dose therapeutics is a growing trend as promising new highly potent therapeutic agents are developed. Compounds deemed "highly potent" in pharmaceutical pipelines today describe nearly half of all market approved products and half of the small molecules currently advancing in clinical studies. Therefore, understanding how Read more
WEST LAFAYETTE, Ind., Nov. 9, 2023 /PRNewswire-PRWeb/ -- Amorphous drugs have become a critical component in modern medicine and in drug development pipelines. Understanding the structural basis of phase stability of these materials is critical in the design of drug products, and yet remains a challenge due to the limited availability of high-resolution analytical tools. In Read more
WEST LAFAYETTE, Ind., Oct. 10, 2023 /PRNewswire-PRWeb Starting Monday, October 23rd at 12:30 PM, Dr. Susan-Bogdanowich-Knipp, President of Ravine Pharmaceuticals and Consultant with Improved Pharma, will present "Physical Evaluation of Late Appearing Polymorph of Ritonavir Form III." The physico-chemical characterization of the recently-prepared Ritonavir, Form III will be described. The full poster can be accessed Read more
Improved Pharma is pleased to announce that their ritonavir research with Varda Space Industries that was published earlier this year has been selected by Organic Process Research & Development as one of the top “remarkable accomplishments from the scientific literature that are expected to be relevant and important with future practical applications”. A brief summary of the work, along with other highlighted Read more
To enhance the solubility of orally administered pharmaceuticals, liquid capsules or amorphous tablets are often preferred over crystalline drug products. However, little is known regarding the variation in bonding mechanisms between pharmaceutical molecules in their different disordered forms. In this study, liquid and melt-quenched glassy carbamazepine have been studied using high energy X-ray diffraction and Read more
WEST LAFAYETTE, IND. (PRWEB) SEPTEMBER 27, 2022 Improved Pharma is presenting their research on all three days of the AAPS conference. On Monday October 17th at 2:30 pm, please visit monitor #31 in forum 6. Ms. Ruba Alajlouni will present “Feasibility of Synchrotron XRD for the analysis of mixture sub-samples.” She will share results demonstrating the effective Read more
WEST LAFAYETTE, Ind. (PRWEB)September 13, 2022 Developing new tools and advancing pharmaceutical development is a key part of Improved Pharma’s mission. In 2021, Improved Pharma had the unique opportunity to start polymorph screening research projects in close collaboration with Varda Space Industries with the intent of advancing pharmaceutical product manufacturing. As a result, the Read more
WEST LAFAYETTE, IND. (PRWEB) JANUARY 03, 2022 Improved Pharma’s continued collaboration with expert colleagues in the field of amorphous studies has resulted in a new publication. The article can be downloaded for free by clicking on this link. This free access expires on February 11, 2022. This article highlights the extreme value of using synchrotron x-ray Read more
WEST LAFAYETTE, Ind. (PRWEB)October 15, 2021 Starting Monday, October 18th, Dr. Susan-Bogdanowich-Knipp, President of Ravine Pharmaceuticals and consultant with Improved Pharma, will present “Polymorph Screen of Newly Discovered Salts of Bedaquiline”. The poster (M2142) is part of the Manufacturing and Analytical Characterization – Chemical – Drug Substance Manufacturing and Development – Crystal Structure/Polymorph Screening Read more
