Improved Pharma Contributes to Paper Advancing the Study of Sameness of Amorphous Materials

WEST LAFAYETTE, IND. (PRWEB) JANUARY 03, 2022 Improved Pharma’s continued collaboration with expert colleagues in the field of amorphous studies has resulted in a new publication. The article can be downloaded for free by clicking on this link. This free access expires on February 11, 2022. This article highlights the extreme value of using synchrotron x-ray Read more

Improved Pharma Contributes to Paper Advancing the Study of Sameness of Amorphous Materials2022-01-17T20:22:19+00:00

Improved Pharma presenting at AAPS 2021 PHARMSCI 360 with Four Posters

WEST LAFAYETTE, Ind. (PRWEB)October 15, 2021 Starting Monday, October 18th, Dr. Susan-Bogdanowich-Knipp, President of Ravine Pharmaceuticals and consultant with Improved Pharma, will present “Polymorph Screen of Newly Discovered Salts of Bedaquiline”. The poster (M2142) is part of the Manufacturing and Analytical Characterization – Chemical – Drug Substance Manufacturing and Development – Crystal Structure/Polymorph Screening Read more

Improved Pharma presenting at AAPS 2021 PHARMSCI 360 with Four Posters2022-01-17T20:23:59+00:00

Additional Research on Bedaquiline Salts recently published in Acta Crystallographica

Improved Pharma is pleased to announce an additional open-source publication describing the structures of Bedaquiline maleate salts that is now available to download.  Previously, our lab was able to identify promising new benzoate salts of Bedaquiline, a first-in-class drug used in the treatment of tuberculosis.  This current publication describes the successfully solved crystal structures obtained from Read more

Additional Research on Bedaquiline Salts recently published in Acta Crystallographica2022-01-17T20:25:52+00:00

Improved Pharma announces recent publication on expediting preclinical formulation development of amorphous lapatinib using mini-tab formulations in pediatrics

Dr, Stephen Byrn, CSO of Improved Pharma, was a key contributor to a recent publication describing the usefulness of mini-tablets in monitoring the dose-response of lapatinib solid amorphous dispersions in juvenile pigs.   Juvenile pigs have been well-established as an effective pediatric model.  The use of mini-tabs allowed for dose flexibility as the the amount of tablets dosed could Read more

Improved Pharma announces recent publication on expediting preclinical formulation development of amorphous lapatinib using mini-tab formulations in pediatrics2022-01-17T20:26:32+00:00

Improved Pharma announces new publication on amorphous dispersions

A recent collaboration with our colleagues further advances the field of X-ray pair distribution function analysis applied to the analysis of amorphous solid dispersions. In this paper, we present the results of different polymer:flubendazole drug dispersions exposed to aging conditions. We discovered that if the polymer has ion-base interactions with the drug, the resulting Read more

Improved Pharma announces new publication on amorphous dispersions2022-01-17T20:27:17+00:00

Recent research on bedaquiline selected for the November cover of Acta Crystallographic

Improved Pharma is pleased to announce the open-source publication of research into finding new salts of bedaquiline, an important drug for the treatment of tuberculosis. The drug is currently marketed in the US as the fumarate salt. Our team discovered several new salts, and the crystal structures of two benzoate salts are described in Read more

Recent research on bedaquiline selected for the November cover of Acta Crystallographic2022-01-17T20:39:31+00:00

Improved Pharma presenting at AAPS 2020 PHARMSCI 360 with Rapid Fire Presentation and Poster

WEST LAFAYETTE, IND. (PRWEB) OCTOBER 26, 2020 Interact with us via poster number 924440 and the Advances and Innovation in Formulation Development Rapid Fire session. On Wednesday October 28th, Dr. Pamela Smith, COO of Improved Pharma, will present “Synchrotron-Based Formulation Development” in the Rapid Fire: Formulation and Quality – Chemical session. Those registered for the meeting Read more

Improved Pharma presenting at AAPS 2020 PHARMSCI 360 with Rapid Fire Presentation and Poster2020-10-26T17:34:00+00:00

Published book chapter on Solid-State Characterization

Improved Pharma COO Pamela Smith is co-author of a chapter in the latest edition of Specification of Drug Substances and Products: Development and Validation of Analytical Methods. The chapter, Solid-State Characterization – Method Development and Validation, focuses on the key issues that must be addressed when developing solid-state methods. Method development and validation for pharmaceuticals Read more

Published book chapter on Solid-State Characterization2022-01-17T20:40:53+00:00

Improved Pharma Announces New Collaborations Enabling Expansion Of Services

WEST LAFAYETTE, IND. (PRWEB) JULY 20, 2020 Improved Pharma is pleased to announce new collaborations with Westport Pharmaceutical Consulting, LLC (dba WPC, LLC) and Ravine Pharmaceuticals LLC enabling expansion of expertise and service offerings to the pharmaceutical industry in support of drug substance and drug product development. These additions bring a vast amount of relevant Read more

Improved Pharma Announces New Collaborations Enabling Expansion Of Services2022-01-17T20:29:32+00:00

Learn about Improved Pharma’s approach to polymorph and salt screening

Polymorph screens and salt screens are important components for drug development. The goal of polymorph screening is to try to find all possible crystal forms by small-scale crystallization and to select a stable form that can be manufactured and formulated into a dosage form. Salt screens are commonly used to alter the physicochemical properties of Read more

Learn about Improved Pharma’s approach to polymorph and salt screening2020-07-15T20:52:18+00:00
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