WEST LAFAYETTE, IND. (PRWEB) JULY 19, 2019 Improved Pharma LLC announces the upcoming presentation of “Continuity of Solids between Amorphous and Crystalline States – Insights from Synchrotron X-ray Pair Distribution (SXPDF) Studies”. The authors are Stephen R. Byrn and Pamela A. Smith of Improved Pharma, along with Chris Benmore of Argonne National Laboratory and Gabriel de Read more
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DOWNLOAD THIS WHITE PAPER AS A PDF BY CLICKING ON THIS LINK The abuse and misuse of prescription opioid products is a serious and growing public health problem. Opioid products are often manipulated to bypass extended-release (ER) properties. As such, the FDA is encouraging the development of opioid formulations that are more difficult to abuse Read more
WEST LAFAYETTE, IND. (PRWEB) JUNE 10, 2019 Improved Pharma LLC announces the publication of “Predictive and Accelerated Formulation Design Using Synchrotron Methods” in the July 2019 issue of AAPS PharmSciTech. The article was published online on April 29th, 2019. The authors are Stephen R. Byrn and Pamela A. Smith of Improved Pharma, along with Xiaoming Sean Chen of Read more
Improved Pharma and Excelsus Structural Solutions (Swiss) AG are continuing their collaboration to better enable access to synchrotron facilities for industrial clients, especially for pharmaceutical R&D. At the conference, we discussed recent scientific advances, provided instruction on XRPD and pairwise distribution function (PDF) analysis, and facilitated discussions focused on establishing guidelines for the analysis of Read more
Smith1, C.J. Benmore2, J.K.R. Weber2,3 and S.R. Byrn1. 1) Improved Pharma, West Lafayette, IN 47906, USA 2) X-Ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA 3) Materials Development, Inc., Arlington Heights, IL 60004, USA The kinetics and disorder of hydration (or dehydration) of pharmaceutical hydrates is of the utmost importance Read more
May is speed month here in Indiana, home of the Indy 500. Improved Pharma is celebrating speed month by highlighting services that help you speed your drug development and reduce time to market. Importantly, it is Improved Pharma’s expertise and scientific knowledge that is the key to faster, cheaper drug development. We have a range Read more
Improved Pharma LLC will be exhibiting in booth 551, conveniently located in the center of the Formulation and Quality section next to one of the Poster Forums. We look forward to meeting with you to discuss the latest advances in pharmaceutical research and development. Have a problem with solubility or bioavailability? Want to reformulate your Read more
As changes are made to the manufacturing process during drug development, it is often necessary to ensure that a drug or drug product made in a new way is the same as the material produced using the original methods. These equivalence studies often focus on chemical or physical properties and are relatively straight-forward for well-defined, Read more
Laboratory powder diffraction is a proven and trusted technique for pharma R&D but synchrotron powder diffraction pushes beyond the capabilities of conventional instrumentation. SPS-XRPD is joining with PPXRD to highlight the most exciting recent developments and opportunities in pharmaceutical R&D made possible by synchrotron XRPD. The joint meeting offers the chance to engage an active Read more
One of the most critical parts of drug discovery and development is identifying the structure of the drug substance and drug product. For crystalline materials and biologicals it is routine to determine the arrangement of covalent bonds in the drug substance and drug product and the structure of the solid forms of the drug substance. Read more