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So far Ed olimpio has created 81 blog entries.

Co-processed Pharmaceutical Solids – An Approach to Screening by Steve Byrn

Co-processed pharmaceutical solids are of considerable interest because of the improvements co-processing can make in a number of solid state properties and pharmaceutical processes. Our first blog on this topic provided a general introduction to co-processed pharmaceutical solids. Examples of crystallization methods with a second component, spherical crystallization, HME prepared solids, and co-processing with Read more

Co-processed Pharmaceutical Solids – An Approach to Screening by Steve Byrn2024-03-12T17:25:07+00:00

Improved Pharma analyzing pharmaceuticals crystallized in space

WEST LAFAYETTE, Ind., Feb. 26, 2024 /PRNewswire-PRWeb/ -- Varda's/close partner's satellite "W-1" was launched into space to demonstrate Varda's spacecraft & reentry capabilities and pharmaceutical hardware functionality, paving the way for microgravity-enabled drug development. While in low earth orbit, melt/cool experiments were successfully conducted on ritonavir. Varda's capsule successfully touched down in the Utah Desert Read more

Improved Pharma analyzing pharmaceuticals crystallized in space2024-02-26T16:39:26+00:00

Improved Pharma Brings Onboard Micro-DSC Hot-Stage System with Imaging Capabilities for Obtaining Thermal Properties of Micro-Quantities of Materials

WEST LAFAYETTE, Ind., Feb. 12, 2024 /PRNewswire-PRWeb/ -- Improved Pharma is pleased to announce expanded capabilities in collaboration with Chemical Microscopy for evaluating the thermal properties of micro-quantities of materials. The newly-added Mettler-Toledo HS84/HS1 DSC controller micro-DSC system is the only true DSC hot stage on the market, and will allow visual observation of thermal events when only Read more

Improved Pharma Brings Onboard Micro-DSC Hot-Stage System with Imaging Capabilities for Obtaining Thermal Properties of Micro-Quantities of Materials2024-02-13T15:27:11+00:00

Joint research collaboration with Chemical Microscopy, LLC featured in the “Improving Product Quality & Material Understanding” special issue of Pharmaceutical Research

WEST LAFAYETTE, Ind., Jan. 26, 2024 /PRNewswire-PRWeb/ -- Research for low-dose therapeutics is a growing trend as promising new highly potent therapeutic agents are developed. Compounds deemed "highly potent" in pharmaceutical pipelines today describe nearly half of all market approved products and half of the small molecules currently advancing in clinical studies. Therefore, understanding how Read more

Joint research collaboration with Chemical Microscopy, LLC featured in the “Improving Product Quality & Material Understanding” special issue of Pharmaceutical Research2024-01-26T14:30:50+00:00

Co-processed Pharmaceutical Solids – A General Introduction by Steve Byrn

Co-processed pharmaceutical solids are rising to the forefront as an important concept in pharmaceutical development. This general introduction is the first in a planned series of blogs delving into this exciting area. Schenck and coworkers reviewed co-processed API, suggesting co-processing would lead to sustainability improvements and emissions reductions. (Schenck et al., 2023) He indicated Read more

Co-processed Pharmaceutical Solids – A General Introduction by Steve Byrn2024-01-23T13:25:47+00:00

Joint research collaboration between Merck, Purdue University, Argonne National Laboratory, and Improved Pharma

WEST LAFAYETTE, Ind., Nov. 9, 2023 /PRNewswire-PRWeb/ -- Amorphous drugs have become a critical component in modern medicine and in drug development pipelines. Understanding the structural basis of phase stability of these materials is critical in the design of drug products, and yet remains a challenge due to the limited availability of high-resolution analytical tools. In Read more

Joint research collaboration between Merck, Purdue University, Argonne National Laboratory, and Improved Pharma2023-11-09T21:38:11+00:00

Improved Pharma at AAPS 2023 PHARMSCI 360 with booth #3323, two posters, and an invited talk as a Speaker Spotlight

WEST LAFAYETTE, Ind., Oct. 10, 2023 /PRNewswire-PRWeb  Starting Monday, October 23rd at 12:30 PM, Dr. Susan-Bogdanowich-Knipp, President of Ravine Pharmaceuticals and Consultant with Improved Pharma, will present "Physical Evaluation of Late Appearing Polymorph of Ritonavir Form III." The physico-chemical characterization of the recently-prepared Ritonavir, Form III will be described. The full poster can be accessed Read more

Improved Pharma at AAPS 2023 PHARMSCI 360 with booth #3323, two posters, and an invited talk as a Speaker Spotlight2023-10-10T12:23:19+00:00

Improved Pharma Enhances Solid-State Analytical Capabilities with Cutting-Edge Empyrean X-ray Diffractometer

WEST LAFAYETTE, Ind., Oct. 2, 2023 /PRNewswire-PRWeb/  Improved Pharma is pleased to announce it has recently purchased a Malvern PANalytical Empyrean Multi-Purpose X-ray Diffractometer. This instrument is housed in their new laboratory expansion area and supports their growing research and development business. CSO Stephen Byrn explains "X-ray Powder Diffraction (XRPD) stands as the cornerstone of solid-state form analysis, Read more

Improved Pharma Enhances Solid-State Analytical Capabilities with Cutting-Edge Empyrean X-ray Diffractometer2023-10-04T19:59:49+00:00

Improved Pharma expands laboratory space by 50% to accommodate recent growth in our research and development programs

WEST LAFAYETTE, Ind., Sept. 14, 2023 /PRNewswire-PRWeb/ -- Improved Pharma is pleased to announce it has recently expanded into adjacent laboratory space in the Purdue Kurz Technology Center. This expansion is the second since first acquiring laboratory space in 2020. The lab was also expanded in 2021. Business has increased more than 800% since 2019, driving the lab expansion. Read more

Improved Pharma expands laboratory space by 50% to accommodate recent growth in our research and development programs2023-09-14T14:37:47+00:00
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