The 4th Spring Pharmaceutical Synchrotron X-Ray Powder Diffraction Workshop was held June 10-11, 2024, at the Novartis campus in Basel, Switzerland. The SPS-XRPD workshops are a collaborative effort between Excelsus Structural Solutions in Switzerland and Purdue University, Argonne National Laboratory, and Improved Pharma in the United States. These workshops bring together experts from the Read more
WEST LAFAYETTE, Ind., July 15, 2024 /PRNewswire-PRWeb/ -- Improved Pharma is pleased to announce it has recently purchased an Agilent 1290 Infinity II LC System. This instrument is housed in their chromatography laboratory and supports their growing research and development business. Compared to conventional high-performance liquid chromatography (HPLC), ultrahigh-performance liquid chromatography (UHPLC) offers higher Read more
This blog focuses on how microscopy, hot-stage microscopy, and DSC microscopy can be used to develop co-processing strategies and relies heavily on input from Chemical Microscopy LLC, which is closely linked to Improved Pharma. Micro approaches are ideal when only limited amounts of material are available. Micro approaches also have the distinct advantage of Read more
WEST LAFAYETTE, Ind., July 11, 2024 /PRNewswire-PRWeb/ -- Improved Pharma is pleased to announce a new collaboration with John Torchia of Asterane Pharma LLC. John brings 20 years of experience in the pharmaceutical industry, specializing in UPLC / HPLC and LC-MS/MS method development and characterization of APIs, drug products, and biologics. He also has significant experience in reverse-engineering, Read more
WEST LAFAYETTE, Ind., June 18, 2024 /PRNewswire-PRWeb/ -- Improved Pharma is pleased to announce it has expanded by adding a dedicated microscopy laboratory adjacent to its existing laboratory space in the Kurz Technology Center at the Purdue University Research Park. This expansion is the third since first acquiring laboratory space in 2020. The lab was Read more
Our first blog post on co-processed pharmaceutical solids provided a general introduction. A second blog discussed an approach to screening for co-processed pharmaceutical solids. This third blog focuses on analytical methods for studying co-processed pharmaceutical solids. Analytical methods for co-processed compositions are particularly important to verify the formation of the composition and provide a Read more
WEST LAFAYETTE, Ind., March 22, 2024 /PRNewswire-PRWeb/ -- Improved Pharma and Varda Space Industries have published the first mission results in ChemRxiv in an article entitled Return of the Ritonavir: A Study on the Stability of Pharmaceuticals Processed in Orbit and Returned to Earth. The team reports that the most stable form of ritonavir (Form II) Read more
Co-processed pharmaceutical solids are of considerable interest because of the improvements co-processing can make in a number of solid state properties and pharmaceutical processes. Our first blog on this topic provided a general introduction to co-processed pharmaceutical solids. Examples of crystallization methods with a second component, spherical crystallization, HME prepared solids, and co-processing with Read more
WEST LAFAYETTE, Ind., Feb. 26, 2024 /PRNewswire-PRWeb/ -- Varda's/close partner's satellite "W-1" was launched into space to demonstrate Varda's spacecraft & reentry capabilities and pharmaceutical hardware functionality, paving the way for microgravity-enabled drug development. While in low earth orbit, melt/cool experiments were successfully conducted on ritonavir. Varda's capsule successfully touched down in the Utah Desert Read more
WEST LAFAYETTE, Ind., Feb. 12, 2024 /PRNewswire-PRWeb/ -- Improved Pharma is pleased to announce expanded capabilities in collaboration with Chemical Microscopy for evaluating the thermal properties of micro-quantities of materials. The newly-added Mettler-Toledo HS84/HS1 DSC controller micro-DSC system is the only true DSC hot stage on the market, and will allow visual observation of thermal events when only Read more
