Dr, Stephen Byrn, CSO of Improved Pharma, was a key contributor to a recent publication describing the usefulness of mini-tablets in monitoring the dose-response of lapatinib solid amorphous dispersions in juvenile pigs.   Juvenile pigs have been well-established as an effective pediatric model.  The use of mini-tabs allowed for dose flexibility as the the amount of tablets dosed could be easily controlled, which is critical to maintaining the desired dose level and plasma concentration in pediatric patients.  Click below to view the article.