This blog focuses on how microscopy, hot-stage microscopy, and DSC microscopy can be used to develop co-processing strategies and relies heavily on input from Chemical Microscopy LLC, which is closely linked to Improved Pharma. Read more
Our first blog post on co-processed pharmaceutical solids provided a general introduction. A second blog discussed an approach to screening for co-processed pharmaceutical solids. This third blog focuses on analytical methods for studying co-processed Read more
Co-processed pharmaceutical solids are of considerable interest because of the improvements co-processing can make in a number of solid state properties and pharmaceutical processes. Our first blog on this topic provided a general introduction Read more
Co-processed pharmaceutical solids are rising to the forefront as an important concept in pharmaceutical development. This general introduction is the first in a planned series of blogs delving into this exciting area. Schenck and Read more
DSC is a powerful method for the analysis of a range of materials. A typical DSC experiment measures the heat changes that occur within the sample when the temperature is changed. For the analysis, Read more
Pharmaceutical materials can exist in a crystalline or amorphous state. Figure 1 illustrates the crystalline state as a perfectly ordered solid with molecules (circles) packed in an orderly array. Figure 1 also illustrates an Read more
Since the ritonavir crisis in 1998, when a lifesaving HIV protease inhibitor had to be withdrawn from the market for almost a year due to a sudden and unpredictable appearance of a new less soluble Read more
In the early 1990’s SSCI, Inc. began working with Parke-Davis Warner-Lambert by providing X-ray diffraction measurements on samples manufactured at its Holland, Michigan manufacturing facility. One of the compounds under investigation was atorvastatin calcium. Atorvastatin Read more
Crystals were observed growing within a DayQuil Liquicap. This blog post describes the approach taken to isolate and identify the unknown crystals. Vicks® DayQuil™ Severe Cold & Flu provides an over the counter non-drowsy, Read more
Come see us at booth 555 and posters T1430-08-45 and T1430-08-46 Improved Pharma will be exhibiting in booth 555, conveniently located next to the 360 Center Stage. Also, Dr. Susan Bogdanowich-Knipp and Dr. Pamela Read more
