Improved Pharma Publishes Review Article in AAPS PharmSciTech

WEST LAFAYETTE, IND. (PRWEB) JUNE 10, 2019 Improved Pharma LLC announces the publication of “Predictive and Accelerated Formulation Design Using Synchrotron Methods” in the July 2019 issue of AAPS PharmSciTech. The article was published online on April 29th, 2019. The authors are Stephen R. Byrn and Pamela A. Smith of Improved Pharma, along with Xiaoming Sean Chen of Read more

Improved Pharma Publishes Review Article in AAPS PharmSciTech2020-04-30T19:06:37+00:00

Advances in synchrotron XRPD in the pharmaceutical industry discussed at SPS-XRPD-2 and PPXRD-16

Improved Pharma and Excelsus Structural Solutions (Swiss) AG are continuing their collaboration to better enable access to synchrotron facilities for industrial clients, especially for pharmaceutical R&D.  At the conference, we discussed recent scientific advances, provided instruction on XRPD and pairwise distribution function (PDF) analysis, and facilitated discussions focused on establishing guidelines for the analysis of Read more

Advances in synchrotron XRPD in the pharmaceutical industry discussed at SPS-XRPD-2 and PPXRD-162020-04-30T19:07:13+00:00

Humidity Effects on Amorphous Pharmaceuticals

Smith1, C.J. Benmore2, J.K.R. Weber2,3 and S.R. Byrn1. 1) Improved Pharma, West Lafayette, IN 47906, USA 2) X-Ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA 3) Materials Development, Inc., Arlington Heights, IL 60004, USA The kinetics and disorder of hydration (or dehydration) of pharmaceutical hydrates is of the utmost importance Read more

Humidity Effects on Amorphous Pharmaceuticals2020-04-30T19:08:10+00:00

Speed Your Drug Development Using Improved Pharma’s Services

May is speed month here in Indiana, home of the Indy 500.  Improved Pharma is celebrating speed month by highlighting services that help you speed your drug development and reduce time to market.  Importantly, it is Improved Pharma’s expertise and scientific knowledge that is the key to faster, cheaper drug development.  We have a range Read more

Speed Your Drug Development Using Improved Pharma’s Services2020-04-30T19:08:42+00:00

Come meet us at AAPS 2019 PHARMSCI 360!

Improved Pharma LLC will be exhibiting in booth 551, conveniently located in the center of the Formulation and Quality section next to one of the Poster Forums. We look forward to meeting with you to discuss the latest advances in pharmaceutical research and development.  Have a problem with solubility or bioavailability?  Want to reformulate your Read more

Come meet us at AAPS 2019 PHARMSCI 360!2020-04-30T19:09:08+00:00

Detecting Differences In Formulations

As changes are made to the manufacturing process during drug development, it is often necessary to ensure that a drug or drug product made in a new way is the same as the material produced using the original methods. These equivalence studies often focus on chemical or physical properties and are relatively straight-forward for well-defined, Read more

Detecting Differences In Formulations2020-04-30T19:09:57+00:00

Improved Pharma representatives to present and teach at SPS-XRPD summit

Laboratory powder diffraction is a proven and trusted technique for pharma R&D but synchrotron powder diffraction pushes beyond the capabilities of conventional instrumentation. SPS-XRPD is joining with PPXRD to highlight the most exciting recent developments and opportunities in pharmaceutical R&D made possible by synchrotron XRPD. The joint meeting offers the chance to engage an active Read more

Improved Pharma representatives to present and teach at SPS-XRPD summit2020-04-30T19:10:39+00:00

Structure of Amorphous Materials – Structure Determination Service

One of the most critical parts of drug discovery and development is identifying the structure of the drug substance and drug product. For crystalline materials and biologicals it is routine to determine the arrangement of covalent bonds in the drug substance and drug product and the structure of the solid forms of the drug substance. Read more

Structure of Amorphous Materials – Structure Determination Service2020-04-30T19:11:22+00:00

AAPS Poster – Presented at AAPS

Non-crystalline phases such as amorphous states can lead to increased solubility for drugs.  However, amorphous materials are notoriously unstable and tend to crystallize over time.  As such, many amorphous materials are created in a dispersion with a polymer to increase their physical stability.  X-ray powder diffraction patterns of amorphous materials are broad and not useful Read more

AAPS Poster – Presented at AAPS2020-04-30T19:12:07+00:00

Drug Delivery Device Summit Presentation

Current approaches to accelerated drug development typically involve parallel track activities utilizing sophisticated project management capabilities.  Improved Pharma has developed a strategy that continues to utilize these project management tools but in addition utilizes predictive tools based on structure analysis of formulations and anticipation of major instabilities of formulations by assessing formulation risk.  Orphan drugs Read more

Drug Delivery Device Summit Presentation2020-04-30T19:16:56+00:00
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