Latest Publications
Increasing the Effectiveness of Slurry Experiments to Confirm the Relative Stability of Polymorphs
Thermodynamic stability and form selection. Form selection of active pharmaceutical ingredients is regarded as an essential part of drug development. The goal of form selection is to identify the most suitable solid form forRead more
Improved Pharma Expands Service Offerings with Addition of VTI Corp. SGA-100 DVS for Measurement of Hygroscopicity
Improved Pharma is pleased to announce expanded capabilities with the addition of an in-house SGA-100 DVS. DVS is very useful in understanding if material is hygroscopic, and subsequently if it will lose the adsorbedRead more
Patenting and Litigating Pharmaceutical Salts
On Thursday, April 28, at 12:30 PM ET, please join Gene Quinn, President & CEO of IPWatchdog, Inc., and our distinguished panel consisting of Dr. Stephen Byrn of Purdue University and Improved Pharma, Dr. Steven Zeman, partner and European andRead more
Improved Pharma returns to Sustainable Medicines in Africa Program
The Sustainable Medicines in Africa program, which includes a master’s degree in biotechnology innovation and regulatory science from Purdue University, returned to Arusha, Tanzania in March of 2022. About 100 students and instructors gatheredRead more
Determining the Transition Temperature of Enantiotropic Polymorphs with Slow Transformation Kinetics
Select the polymorph with attributes fit for development. It is well established that polymorphism is common in pharmaceutical active ingredients.1 Bernstein and others present statistics that, when they are appropriately screened up to threeRead more
Detecting Small Amounts of a Polymorph or Solid Form in Drug Product
How to quantitate a solid form in your drug product. A very important aspect of pharmaceutical mixture analysis is detecting and possibly quantitating a specific solid form in a drug product, especially tablets. ChapterRead more