Latest Publications
The High-Quality Difference: Solid-State Data That Stands Up to FDA and Patent Review
Authors Jared Smit, David Engers, Steve Byrn In modern small-molecule development, solid-state characterization is far more than a routine analytical task.(Byrn, Zografi et al. 2025) It defines the manufacturable form of an API, supportsRead more
Publication of Crystal Structure of Ritonavir Form IV and Thermodynamic Relationships between Ritonavir Polymorphs
WEST LAFAYETTE, Ind., Jan. 27, 2026 /PRNewswire/ -- Improved Pharma is pleased to share that our research on the crystal structure of Ritonavir Form IV has been published in the highly reputable and peer-reviewed journal, CrystalRead more
New Edition of Seminal Text “Solid-State Materials in Pharmaceutical Chemistry” Released by Industry Leaders
The updated second edition delivers expanded insights into solid-state pharmaceutical materials, reflecting major scientific and regulatory advances in drug development. WEST LAFAYETTE, Ind., Jan. 7, 2026 /PRNewswire/ -- Improved Pharma is proud to announce the releaseRead more
Improved Pharma exhibiting and presenting at AAPS 2025 PHARMSCI 360
Meet us at Booth #3561 and posters M1030-04-26, M1330-08-54, and T1130-02-10. WEST LAFAYETTE, Ind. , Oct. 23, 2025 /PRNewswire/ -- This year, Improved Pharma occupies a larger corner booth (#3561) shared with Varda Space Industries (#3563).Read more
Seeing Solids Clearly—Beyond Powder Patterns with Single-Crystal X-ray Diffraction for Polymorphs, Hydrates, and IP Confidence: How Improved Pharma Uses SCXRD
Single-crystal X-ray diffraction (SCXRD) provides the most definitive structural picture of pharmaceutical solids. From a single crystal, we obtain the unit cell, space group, and full atomic coordinates, which reveal hydrogen-bonding networks, π–π (ring)Read more
Reduced Dose Formulations
Steve Byrn, September 26, 2025 Reduced dose formulations provide one of the most exciting approaches to improving medicines by reducing side effects, pill burden, and drug load in the patient and by reducing costRead more
Solving Pharmaceutical Problems
We are a research and information company dedicated to improving pharmaceutical methods, formulations, and processes.