Achieving control is essential in early-stage pharmaceutical development, not only to meet regulatory expectations but to ensure consistency, high-quality, and reliability of clinical batches. Improved Pharma has developed a comprehensive control strategy that supports Read more
This blog series will address regulatory problem-solving. Our expertise spans preclinical to market, supporting regulatory submissions, application reviews, and post-approval changes (PAC). Our senior experts have over 200 years of combined experience, including service Read more
Dr. Chris Benmore of Argonne National Laboratory delivered an insightful talk at the 4th Spring Pharmaceutical Synchrotron X-Ray Powder Diffraction Workshop held June 10-11, 2024, at the Novartis campus in Basel, Switzerland. His presentation Read more
The 4th Spring Pharmaceutical Synchrotron X-Ray Powder Diffraction Workshop was held June 10-11, 2024, at the Novartis campus in Basel, Switzerland. The SPS-XRPD workshops are a collaborative effort between Excelsus Structural Solutions in Switzerland Read more
This blog focuses on how microscopy, hot-stage microscopy, and DSC microscopy can be used to develop co-processing strategies and relies heavily on input from Chemical Microscopy LLC, which is closely linked to Improved Pharma. Read more
Our first blog post on co-processed pharmaceutical solids provided a general introduction. A second blog discussed an approach to screening for co-processed pharmaceutical solids. This third blog focuses on analytical methods for studying co-processed Read more
Co-processed pharmaceutical solids are of considerable interest because of the improvements co-processing can make in a number of solid state properties and pharmaceutical processes. Our first blog on this topic provided a general introduction Read more
Co-processed pharmaceutical solids are rising to the forefront as an important concept in pharmaceutical development. This general introduction is the first in a planned series of blogs delving into this exciting area. Schenck and Read more
DSC is a powerful method for the analysis of a range of materials. A typical DSC experiment measures the heat changes that occur within the sample when the temperature is changed. For the analysis, Read more
Pharmaceutical materials can exist in a crystalline or amorphous state. Figure 1 illustrates the crystalline state as a perfectly ordered solid with molecules (circles) packed in an orderly array. Figure 1 also illustrates an Read more
