Come see us at booth 555 and posters T1430-08-45 and T1430-08-46
Improved Pharma will be exhibiting in booth 555, conveniently located next to the 360 Center Stage. Also, Dr. Susan Bogdanowich-Knipp and Dr. Pamela Smith will be presenting posters on Tuesday afternoon from 2:30 – 3:30. The presentations will be held in Forum 8, located immediately across from the Improved Pharma booth.
Dr. Bogdanowich-Knipp will be presenting “Green Chemistry Initiative for Formulation, Pressing, and Evaluating Tablets in Low-Resource Settings”. This poster showcases some of the work done at the Sustainable Medicines in Africa program held in March, 2022. For a hands-on laboratory with the students, locally sourced ingredients were used to prepare wet granulated formulations that easily demonstrated the variability in granule size and behavior with different formulations.
Dr. Smith will present “Using Raman Mapping to Detect and Identify Challenging Degradation Products and Complex Drug-Drug Interactions in a Tablet”. In this poster, an expired pharmaceutical tablet was analyzed. A combination of spatial location, spectral subtractions, and an understanding of reaction chemistry were used to identify degradation products. For example, acetylsalicylic acid (aspirin) can degrade to salicylic acid, which can react with caffeine to form caffeine salicylate. Figure 1 depicts where each compound is present over a 100 micron by 100 micron mapping area.
Figure 1: Each mapping profile is of the same 100 x 100 micron area, with each profile showing the location of aspirin and caffeine (two ingredients in the tablet) and caffeine salicylate (a reaction product).
We will be making more announcements as we get closer to AAPS and we look forward to meeting with you to discuss the latest advances in pharmaceutical research and development. For more information, please contact us at info@improvedpharma.com.