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So far Ed olimpio has created 111 blog entries.

Dissolution-Instrument-Based Strategies to De-Risk and Accelerate Pharmaceutical Development

2026-02-11T21:18:02+00:00

Steve Byrn and David Engers Improved Pharma Feb. 11, 2026 Improved Pharma has recently expanded its dissolution capabilities by installing a fully automated Agilent 708-DS dissolution apparatus paired with the 850-DS autosampler. This capability Read more

Dissolution-Instrument-Based Strategies to De-Risk and Accelerate Pharmaceutical Development2026-02-11T21:18:02+00:00

Improved Pharma Announces Enhanced X-Ray Diffraction and Interpretation Services to Strengthen Market Authorization Applications and Patents

2026-02-11T13:39:59+00:00

Expanded solid-state characterization services now deliver advanced X-ray diffraction, expert interpretation, and regulatory-ready data for market authorization and patents. WEST LAFAYETTE, Ind., Feb. 9, 2026 /PRNewswire/ -- Improved Pharma is pleased to announce the expansion of Read more

Improved Pharma Announces Enhanced X-Ray Diffraction and Interpretation Services to Strengthen Market Authorization Applications and Patents2026-02-11T13:39:59+00:00

The High-Quality Difference: Solid-State Data That Stands Up to FDA and Patent Review

2026-02-02T15:35:43+00:00

Authors Jared Smit, David Engers, Steve Byrn In modern small-molecule development, solid-state characterization is far more than a routine analytical task.(Byrn, Zografi et al. 2025) It defines the manufacturable form of an API, supports Read more

The High-Quality Difference: Solid-State Data That Stands Up to FDA and Patent Review2026-02-02T15:35:43+00:00

Publication of Crystal Structure of Ritonavir Form IV and Thermodynamic Relationships between Ritonavir Polymorphs

2026-01-27T12:59:06+00:00

WEST LAFAYETTE, Ind., Jan. 27, 2026 /PRNewswire/ -- Improved Pharma is pleased to share that our research on the crystal structure of Ritonavir Form IV has been published in the highly reputable and peer-reviewed journal, Crystal Read more

Publication of Crystal Structure of Ritonavir Form IV and Thermodynamic Relationships between Ritonavir Polymorphs2026-01-27T12:59:06+00:00

New Edition of Seminal Text “Solid-State Materials in Pharmaceutical Chemistry” Released by Industry Leaders

2026-01-07T17:53:58+00:00

The updated second edition delivers expanded insights into solid-state pharmaceutical materials, reflecting major scientific and regulatory advances in drug development. WEST LAFAYETTE, Ind., Jan. 7, 2026 /PRNewswire/ -- Improved Pharma is proud to announce the release Read more

New Edition of Seminal Text “Solid-State Materials in Pharmaceutical Chemistry” Released by Industry Leaders2026-01-07T17:53:58+00:00

Improved Pharma exhibiting and presenting at AAPS 2025 PHARMSCI 360

2025-10-23T12:11:42+00:00

Meet us at Booth #3561 and posters M1030-04-26, M1330-08-54, and T1130-02-10. WEST LAFAYETTE, Ind. , Oct. 23, 2025 /PRNewswire/ -- This year, Improved Pharma occupies a larger corner booth (#3561) shared with Varda Space Industries (#3563). Read more

Improved Pharma exhibiting and presenting at AAPS 2025 PHARMSCI 3602025-10-23T12:11:42+00:00

Seeing Solids Clearly—Beyond Powder Patterns with Single-Crystal X-ray Diffraction for Polymorphs, Hydrates, and IP Confidence: How Improved Pharma Uses SCXRD

2025-10-07T17:28:23+00:00

Single-crystal X-ray diffraction (SCXRD) provides the most definitive structural picture of pharmaceutical solids. From a single crystal, we obtain the unit cell, space group, and full atomic coordinates, which reveal hydrogen-bonding networks, π–π (ring) Read more

Seeing Solids Clearly—Beyond Powder Patterns with Single-Crystal X-ray Diffraction for Polymorphs, Hydrates, and IP Confidence: How Improved Pharma Uses SCXRD2025-10-07T17:28:23+00:00

Solid State Chemistry of Long-Acting Injectable Suspensions

2025-09-25T23:44:32+00:00

Solid State Chemistry of Long-Acting Injectable Suspensions Steve Byrn September 1, 2025 The Enduring Impact of Long-Acting Injectable Suspensions in Medicine Long-acting injectable (LAI) suspensions play a crucial role in modern drug delivery, offering Read more

Solid State Chemistry of Long-Acting Injectable Suspensions2025-09-25T23:44:32+00:00

Process and Method Validation in IND Drug Development: Building a Robust Foundation

2025-08-26T18:18:37+00:00

In our last blog, we explored the importance of control strategies during early pharmaceutical development. However, two additional elements critical to early-stage Investigational New Drug (IND) applications deserve special attention: process validation and method Read more

Process and Method Validation in IND Drug Development: Building a Robust Foundation2025-08-26T18:18:37+00:00
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