Single-crystal X-ray diffraction (SCXRD) provides the most definitive structural picture of pharmaceutical solids. From a single crystal, we obtain the unit cell, space group, and full atomic coordinates, which reveal hydrogen-bonding networks, π–π (ring) Read more
Steve Byrn, September 26, 2025 Reduced dose formulations provide one of the most exciting approaches to improving medicines by reducing side effects, pill burden, and drug load in the patient and by reducing cost Read more
Solid State Chemistry of Long-Acting Injectable Suspensions Steve Byrn September 1, 2025 The Enduring Impact of Long-Acting Injectable Suspensions in Medicine Long-acting injectable (LAI) suspensions play a crucial role in modern drug delivery, offering Read more
In our last blog, we explored the importance of control strategies during early pharmaceutical development. However, two additional elements critical to early-stage Investigational New Drug (IND) applications deserve special attention: process validation and method Read more
Addition of crystallographer and new instrumentation in support of single crystal structure determination WEST LAFAYETTE, Ind., July 22, 2025 /PRNewswire/ -- Improved Pharma has expanded its capabilities to include in-house single crystal structure determination with the recent acquisition Read more
Improved Pharma is investing in an internal R&D program focused on solid lipid nanoparticles (SLNs). A recent expansion of their research facility included resources dedicated to this endeavor. WEST LAFAYETTE, Ind., July 1, 2025 /PRNewswire/ -- SLNs are a type Read more
WEST LAFAYETTE, Ind., June 6, 2025 /PRNewswire/ -- Improved Pharma LLC is proud to announce the latest milestone in its continued growth with a significant expansion of its laboratory and office facilities at the Read more
Achieving control is essential in early-stage pharmaceutical development, not only to meet regulatory expectations but to ensure consistency, high-quality, and reliability of clinical batches. Improved Pharma has developed a comprehensive control strategy that supports Read more
WEST LAFAYETTE, Ind., March 31, 2025 /PRNewswire/ -- The Spring Synchrotron X-Ray Powder Diffraction (SPS-XRPD) Workshops are a collaborative initiative led by Excelsus Structural Solutions (Switzerland), Purdue University, Argonne National Laboratory, and Improved Pharma (USA). Read more
WEST LAFAYETTE, Ind., Feb. 27, 2025 /PRNewswire/ -- Liquid chromatography coupled with High-Resolution Accurate Mass Spectrometry (LC-HRAMS) is a powerful and flexible technique for the analyses of pharmaceutical drug substances and drug products. The technique separates and identifies Read more
