Amorphous Screening using Levitated Lab on a Drop
Our team has also collaborated over the past few years with Dr. Rick Weber, CEO, of Materials Development, Inc., Evanston, IL and Dr. Chris Benmore of Argonne National lab to levitate drops of organic solvents containing various ratios of drug and polymer. As these drops evaporate, the total X-ray scattering is measured and converted into PDF patterns for analysis. This analysis allows for the rapid determination of the optimum polymer and polymer ratio for scale-up and testing. Thus, Improved Pharma can perform amorphous formulation screens in a rapid and efficient manner. In some cases, standard fast evaporation techniques are also used for Improved Pharma’s amorphous screens.